Rabbit Anti Human HNMT Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot,IHC) from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.02% sodium azide, 50% glycerol, pH7.3 This antibody has been purified using Affinity Purified.

More Details:

• Host: Rabbit
• Species: Human,Mouse
• Target: HNMT
• Clonality: Polyclonal
• Purity: Affinity Purified
• Immunogen: Recombinant fusion protein of human HNMT (NP_008826.1).
• Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

This product can be used in analytical tools such as Western Blot,IHC.

At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.

For research use only.